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Updated: May 3, 2026

A Protocol for Safe Lithiation Reactions Using Organolithium Reagents
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A Protocol for Safe Lithiation Reactions Using Organolithium Reagents

Published on: November 12, 2016

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リチウムアミノアルコシドの溶液構造は,高度にエナチオセレクティブの1,2-添加で使用されます

Angela M Bruneau1, Lara Liou, David B Collum

  • 1Department of Chemistry and Chemical Biology Baker Laboratory, Cornell University , Ithaca, New York 14853-1301, United States.

Journal of the American Chemical Society
|January 30, 2014
PubMed
まとめ

リチウムエフェドラットとノルカラン由来リチウムアミノアルコシドは,テトラメリック構造を形成し,高度にエナチオセレクティブの1,2-添加を可能にします. これらのキラル補助体は,S4対称の立方体コアを示しており,これは大規模合成に不可欠です.

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