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人間のトランスクリプトーム全体におけるRNA二次構造の風景と変異

Yue Wan1, Kun Qu2, Qiangfeng Cliff Zhang3

  • 11] Howard Hughes Medical Institute and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California 94305, USA [2] Stem Cell and Development, Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672 [3].

Nature
|January 31, 2014
PubMed
まとめ

RNA二次構造 (RSSs) は,重要な遺伝子発現情報を持ち,そのほとんどはRNA配列にコードされています. 遺伝的変異はこれらの構造を変化させ,ゲノム全体の遺伝子調節に影響を与える可能性があります.

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