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Updated: May 3, 2026

Imaging the Human Immunological Synapse
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免疫シナプスにおけるT細胞受容体濃縮マイクロベシクルの極化放出

Kaushik Choudhuri1, Jaime Llodrá2, Eric W Roth3

  • 11] Program in Molecular Pathogenesis, Helen L. and Martin S. Kimmel Center for Biology and Medicine of the Skirball Institute of Biomolecular Medicine, 540 First Avenue, New York, New York 10016, USA [2].

Nature
|February 4, 2014
PubMed
まとめ

T細胞受容体 (TCRs) は,TSG101とVPS4によって媒介される細胞外マイクロベシクルを通じて,免疫シナプスセンターから放出されます. これらのマイクロベシクルは,抗原を提示する細胞にTCRを送り出し,T細胞のシグナル伝達と適応免疫を開始します.

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