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Updated: May 3, 2026

Hypothalamic Kisspeptin Neurons as a Target for Whole-Cell Patch-Clamp Recordings
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Hypothalamic Kisspeptin Neurons as a Target for Whole-Cell Patch-Clamp Recordings

Published on: March 17, 2023

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AgRPニューロン回路への刺激性パラバントリキュラー核は,飢餓を駆動する神経回路です

Michael J Krashes1, Bhavik P Shah1, Joseph C Madara2

  • 11] Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA [2] Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA (M.J.K.); National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224, USA (M.J.K.); Cardiovascular and Metabolic Diseases, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, USA (B.P.S.); Division of Pediatric Endocrinology, Departments of Pediatrics, University of Michigan, Ann Arbor, Michigan 48105, USA (D.P.O.); Cardiovascular and Metabolic Diseases, Novartis Institutes for BioMedical Research, 100 Technology Square, Cambridge, Massachusetts 02139, USA (L.V.). [3].

Nature
|February 4, 2014
PubMed
まとめ

研究者らは,食欲を制御する新しい脳の経路を発見した. 垂体下部の特定のニューロンは,チロトロピン放出ホルモン (TRH) と垂体腺酸サイクラゼ活性化ポリペプチド (PACAP) を発現し,アグーティ関連ペプチド (AgRP) ニューロンを活性化して,餌の行動を誘導します.

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