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バクテリオファージHK97の成熟経路のpH誘発の安定性スイッチング

Eric R May1, Karunesh Arora, Charles L Brooks

  • 1Department of Molecular and Cell Biology, University of Connecticut , Storrs, Connecticut 06269, United States.

Journal of the American Chemical Society
|February 6, 2014
PubMed
まとめ

研究者らは,バクテリオファージHK97の成熟をマッピングし,異なるpHレベルでの安定性に影響する重要な残留物を特定しました. これは,DNAの包装がカプシドの再編成をどのように駆動するかを明らかにし,抗ウイルス薬の開発の洞察を提供している.

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