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Updated: May 3, 2026

Measurement of Heme Synthesis Levels in Mammalian Cells
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人工タンパク質におけるヘム共因子の組み立てを工学的に設計する

Lee A Solomon1, Goutham Kodali, Christopher C Moser

  • 1The Johnson Research Foundation, Department of Biochemistry and Biophysics, University of Pennsylvania , Philadelphia, Pennsylvania 19104, United States.

Journal of the American Chemical Society
|February 6, 2014
PubMed
まとめ

研究者は,コファクター結合の障壁に対処することによって,合成タンパク質の組み立てを最適化しました. これにより,ヘムBが人工ヘモプロテインにより迅速に組み込まれ,潜在的な in vivo アプリケーションのための自然な酵素を模倣することができます.

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