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肺の発達,再生,がんにおけるアルベオラ前駆体および幹細胞

Tushar J Desai1, Douglas G Brownfield2, Mark A Krasnow2

  • 11] Department of Biochemistry and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305-5307, USA [2] Department of Internal Medicine, Division of Pulmonary and Critical Care, Stanford University School of Medicine, Stanford, California 94305-5307, USA.

Nature
|February 7, 2014
PubMed
まとめ

出産後,成熟したアルベオラ型2 (AT2) 細胞は幹細胞として機能し,アルベオルを更新し,肺修復と癌に寄与します. この幹細胞機能は,損傷と特定の成長因子信号によって活性化されます.

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