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Updated: May 3, 2026

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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DNAメチルトランスフェラーゼ阻害のための配列特異のDNA結合分子の設計

JeenJoo S Kang1, Jordan L Meier, Peter B Dervan

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

Journal of the American Chemical Society
|February 8, 2014
PubMed
まとめ

研究者らは,DNAメチル化制御のためのCpGサイトを標的とする新しい小分子を開発した. 1つの分子,ヘアピン3は,DNAメチルトランスフェラーゼの活性を効果的に抑制し,新しい表遺伝子療法のための基礎を提供します.

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