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Updated: May 3, 2026

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
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Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

Published on: January 9, 2020

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複雑な特徴の表遺伝的基礎をマッピングする.

Sandra Cortijo1, René Wardenaar, Maria Colomé-Tatché

  • 1Institut de Biologie de l'Ecole Normale Supérieure, Centre National de la Recherche Scientifique (CNRS), UMR 8197, Institut National de la Santé et de la Recherche Médicale (INSERM) U 1024, Paris F-75005, France.

Science (New York, N.Y.)
|February 8, 2014
PubMed
まとめ

エピジェネティックの変化,特にDNAメチレーションは,アラビドプシスの開花時間などの複雑な特性に大きく影響します. これらのエピジェネティック定量特性のロシ (QTL (epi)) は遺伝可能であり,進化的適応を誘導する.

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