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Updated: May 2, 2026

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エピジェノミック変異は,幼児期の致命的なCIMP陽性エペンジモマを定義する

S C Mack1, H Witt2, R M Piro3

  • 11] Developmental & Stem Cell Biology Program, Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada [2] Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada [3] Division of Neurosurgery, University of Toronto, Toronto, Ontario M5S 1A8, Canada [4].

Nature
|February 21, 2014
PubMed
まとめ

ヒンドブレインエペンジモーマは,幼児期の一般的な脳腫瘍で,遺伝的変異は少ないが,表遺伝的変化を示す. これらのエピジェネティック変異をターゲットにすることで,この悪性腫瘍に対する有望な新しい治療戦略が提供されます.

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