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Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
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SIRT2は死滅のために必要ですか?

Kim Newton1, Joanne M Hildebrand2, Zhirong Shen3

  • 1Genentech, Inc., South San Francisco, California 94080, USA.

Nature
|February 28, 2014
PubMed
まとめ

この研究では,プログラム細胞死の一種である死滅におけるSIRT2の役割を調査しました. 研究者らは,SIRT2を阻害または除去することは,細胞を死滅から保護しないことを発見し,この経路におけるその重要性を疑問視した.

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