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環プロペンのサイクロアディションとアヌル化フラン: (+) -と (-) -フロンドーシンBと (+) -フロンドーシンAの総合合成

E Zachary Oblak1, Michael D VanHeyst, Jin Li

  • 1Department of Pharmaceutical Sciences, University of Connecticut , 69 N. Eagleville Road, Storrs, Connecticut 06269, United States.

Journal of the American Chemical Society
|March 1, 2014
PubMed
まとめ

研究者らは,新しいサイクル添加と操作戦略を使用して,フロンドシンAとBの非対称的総合成を達成しました. フロンダソシンAは,フロンダソシンBとは異なり,B細胞系に対する選択的抗増殖活性を示した.

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