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Updated: May 2, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
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Published on: February 28, 2019

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新しいOGT基板のマイクロアレイ発見:メドゥロブラストーマ腫瘍遺伝子OTX2はO-GlcNAcylatedである

Rodrigo F Ortiz-Meoz1, Yifat Merbl, Marc W Kirschner

  • 1Department of Microbiology and Immunobiology, and ‡Department of Systems Biology, Harvard Medical School , Boston, Massachusetts 02115, United States.

Journal of the American Chemical Society
|March 4, 2014
PubMed
まとめ

研究者は,タンパク質マイクロアレイを使用して,O-GlcNAc移転酵素 (OGT) の新しい標的を特定しました. この方法により,転写因子OTX2が新しいOGT基質として発見され,脳発育と腫瘍生成に不可欠である.

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