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Updated: May 2, 2026

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor LATS Biosensor
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ヒッポシグナル伝達はマイクロプロセッサを調節し,細胞密度依存のmiRNAバイオゲネシスをがんとリンクする

Masaki Mori1, Robinson Triboulet2, Morvarid Mohseni3

  • 1Stem Cell Program, Boston Children's Hospital, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Department of Biological Chemistry and Molecular Pharmacology and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Boston, MA 02115, USA.

Cell
|March 4, 2014
PubMed
まとめ

ヒッポ経路は,YAPの調節を通して,マイクロRNA (miRNA) 産生を制御する. このメカニズムは,細胞密度の変化がmiRNAレベルにどのように影響し,がんの発症に寄与するかを説明します.

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