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Updated: May 2, 2026

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
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核ホルモン受容体活性化による転移性メラノーマの幅広いスペクトルの治療抑制

Nora Pencheva1, Colin G Buss1, Jessica Posada1

  • 1Laboratory of Systems Cancer Biology, Rockefeller University, New York, NY 10065, USA.

Cell
|March 4, 2014
PubMed
まとめ

肝臓X核ホルモン受容体 (LXR) をアゴニストで標的にすると,メラノーマの転移を抑制する. LXRβの活性化は,アポリポプロテイン-Eを介して,腫瘍の成長を抑制し,生存を向上させ,新しい治療戦略を提供します.

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