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Updated: May 2, 2026

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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Published on: August 17, 2022

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クラスCのGPCRメタボトロピクグルタミン酸受容体1の構造は,アロステル変調子器に結合する

Huixian Wu1, Chong Wang, Karen J Gregory

  • 1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|March 8, 2014
PubMed
まとめ

研究者らは,ヒトのメタボトロピクグルタミン酸受容体1 (mGlu1) が調節器に結合する構造を明らかにした. これは,クラスCのGタンパク質結合受容体 (GPCRs) のアロステリック調節および活性化メカニズムに関する洞察を明らかにします.

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