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Updated: May 2, 2026

Co-Culture of Murine Small Intestine Epithelial Organoids with Innate Lymphoid Cells
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マクロファージとILC3の微生物群に依存するクロストラックは,腸内ホメオスタシスを促進する

Arthur Mortha1, Aleksey Chudnovskiy, Daigo Hashimoto

  • 1Department of Oncological Sciences, 1470 Madison Avenue, New York, NY 10029, USA.

Science (New York, N.Y.)
|March 15, 2014
PubMed
まとめ

共生微生物は,先天性骨髄性細胞とリンパ性細胞の交差を可能にすることで,免疫ホメオスタシスを促進します. この相互作用は,微生物信号を感知するマクロファージによって駆動され,腸内免疫に不可欠な粒細胞-マクロファージコロニー刺激因子 (GM-CSF) を生成します.

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