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Updated: May 2, 2026

Isolation of Human Monocytes by Double Gradient Centrifugation and Their Differentiation to Macrophages in Teflon-coated Cell Culture Bags
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Isolation of Human Monocytes by Double Gradient Centrifugation and Their Differentiation to Macrophages in Teflon-coated Cell Culture Bags

Published on: September 9, 2014

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ヘム媒介のSPI-C誘導は,単細胞の分化を促進し,鉄をリサイクルするマクロファージになる

Malay Haldar1, Masako Kohyama2, Alex Yick-Lun So3

  • 1Department of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.

Cell
|March 18, 2014
PubMed
まとめ

赤血球の分解産物であるヘムは,臓赤パルプマクロファージ (RPM) と骨髄マクロファージ (BMM) の発育を促します. この発見は,代謝物質主導の免疫細胞の分化と鉄の調節のための新しいメカニズムを明らかにします.

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