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ヘモグロビンのアロステリック変異を単一結晶形式で捉える.

Naoya Shibayama1, Kanako Sugiyama, Jeremy R H Tame

  • 1Division of Biophysics, Department of Physiology, Jichi Medical University , 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan.

Journal of the American Chemical Society
|March 19, 2014
PubMed
まとめ

人間のヘモグロビンは,その緊張 (T) とリラックス (R) の間の複数の中間状態を示します. この研究は,9つの異なるコンフォマーを捕捉し,これまで知られていなかった中介物質とユニークな酸素親和性を明らかにしました.

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