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Updated: May 2, 2026

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
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Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

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一般的なアリルC-Hアルキレーションは,三次核愛素によるものです

Jennifer M Howell1, Wei Liu, Andrew J Young

  • 1Roger Adams Laboratory, Department of Chemistry, University of Illinois at Urbana-Champaign , Urbana, Illinois, 61801, United States.

Journal of the American Chemical Society
|March 20, 2014
PubMed
まとめ

パラジウムで触媒化された新しい方法により,高効率な分子間アリルC−Hアルキル化が,三次核ホルモンを用いて様々なオレフィンに可能になる. この反応は,高収量と選択性を提供し,複雑な分子と自然産物の合成を簡素化します.

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Preparation of Alkynes: Alkylation Reaction

Introduction
Alkylation of terminal alkynes with primary alkyl halides in the presence of a strong base like sodium amide is one of the common methods for the synthesis of longer carbon-chain alkynes. For example, treatment of 1-propyne with sodium amide followed by reaction with ethyl bromide yields 2-pentyne.
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Introduction
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