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Updated: Jun 21, 2026

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
06:54

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細胞表面に発現するTGF-α前駆体は,隣接する細胞のEGF受容体と結合し,信号伝導につながります

S T Wong1, L F Winchell, B K McCune

  • 1Lineberger Cancer Research Center, University of North Carolina School of Medicine, Chapel Hill 27514.

Cell
|February 10, 1989
PubMed
まとめ

成長因子-アルファ (TGF-alpha) の前駆体形態は,完全に処理されていなくても,隣接する細胞の表皮成長因子 (EGF) 受容体を活性化することができます. この膜に結合したproTGF-alphaは,細胞信号伝達経路に影響を与える生物学的活性を示しています.

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