タンパク質とタンパク質の相互作用の検出は,ライシン結合フッ素酸化物の近接性S(N) Ar反応によるものです

David Hymel1, Zachary R Woydziak, Blake R Peterson

  • 1Department of Medicinal Chemistry, The University of Kansas , Lawrence, Kansas 66045, United States.

まとめ

研究者らは,タンパク質とタンパク質の相互作用を検出するための新しいフッ化ピロニンプローブを開発しました. これらの探査機は,インターフェースのライシン残留物間で選択的に転送し,複雑なサンプルにおける生物学的相互作用の識別を可能にします.

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