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Updated: May 1, 2026

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
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Published on: May 22, 2018

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β-アミロイドからのペプチドのオリゴマーのポリモルフィズム

Johnny D Pham1, Borries Demeler, James S Nowick

  • 1Department of Chemistry, University of California, Irvine , Irvine, California 92697-2025, United States.

Journal of the American Chemical Society
|March 28, 2014
PubMed
まとめ

構造の研究は,アミロイドベータ (Aβ) から派生したマクロサイクリックペプチドが,溶液と固体状態で異なるテトラメア構造を形成する方法を示しています. これらの発見は,アルツハイマー病におけるAβオリゴーマー多形性を明らかにするかもしれない.

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