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異なった微生物経路から派生した一時的なネオアンチゲンによるT細胞の活性化

Alexandra J Corbett1, Sidonia B G Eckle1, Richard W Birkinshaw2

  • 11] Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria 3010, Australia [2].

Nature
|April 4, 2014
PubMed
まとめ

粘膜関連不変型T細胞 (MAIT) は,微生物のリボフラビン前駆体によって活性化されます. これらの前駆物質は,他の分子と強力なMAIT活性化抗原を形成し,その後,免疫監視のためにMR1によって提示されます.

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