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Updated: May 1, 2026

Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine
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保護性粘膜免疫は,上皮 CD1d と IL-10 によって媒介されます

Torsten Olszak1, Joana F Neves1, C Marie Dowds2

  • 11] Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA [2].

Nature
|April 11, 2014
PubMed
まとめ

皮質CD1dの結合は,STAT3を活性化させ,IL-10とHSP110の産生につながるので,腸内炎症から保護します. この経路は,炎症性腸疾患における粘膜の恒常性を維持するために重要である.

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