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Updated: May 1, 2026

Live Cell Imaging to Assess the Dynamics of Metaphase Timing and Cell Fate Following Mitotic Spindle Perturbations
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Published on: September 20, 2019

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セントロソーム増幅による細胞侵入の腫瘍遺伝子のような誘導

Susana A Godinho1, Remigio Picone2, Mithila Burute3

  • 11] Howard Hughes Medical Institute, Department of Pediatric Oncology, Dana-Farber Cancer Institute and Pediatric Hematology/Oncology, Children's Hospital, Boston, Massachusetts 02115, USA [2] Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK (S.A.G.); Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455, USA (C.T.L.).

Nature
|April 18, 2014
PubMed
まとめ

センターソームの増幅,つまりセンターソームの増加は,がん細胞の侵入を促進します. この構造の変化は,特に攻撃的な腫瘍では,細胞結合を阻害することによって,腫瘍の進行を促進します.

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