クロマチン繊維の冷凍-EM研究は,テトラヌクレオソーム単位によってねじれた二重ヘリクスを明らかにします

Feng Song1, Ping Chen, Dapeng Sun

  • 1National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

Science (New York, N.Y.)
|April 26, 2014
PubMed
まとめ

この研究は,ヒストンH1と核細胞の重複長が30ナノメートルのクロマチンの繊維構造にどのように影響するかを明らかにしています. この発見は,テトラヌクレオソーム単位の左利き歪みを示し,DNA包装と遺伝子調節の洞察を提供している.

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