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Updated: Aug 2, 2026

Generation of Human Alloantigen-specific T Cells from Peripheral Blood
09:47

Generation of Human Alloantigen-specific T Cells from Peripheral Blood

Published on: November 21, 2014

ペプチドに依存したH-2Kbの認識は,アロ活性型細胞毒性Tリンパ球によって行われます

W R Heath1, M E Hurd, F R Carbone

  • 1Department of Immunology, Scripps Clinic and Research Foundation, La Jolla, California 92037.

Nature
|October 26, 1989
PubMed
まとめ

アロリアクティブT細胞は,メジャー・ヒストコンパティビリティ・コンプレックス (MHC) の分子だけでなく,細胞質タンパク質からのペプチド断片を認識します. この発見は,自己ペプチドがT細胞の認識に役割を果たし,種特有の免疫反応を説明できることを示唆しています.

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