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Updated: May 5, 2026

Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy
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Tatは,新興の標的RNAを介してヒト免疫不全ウイルスをトランス活性化します

B Berkhout1, R H Silverman, K T Jeang

  • 1Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.

Cell
|October 20, 1989
PubMed
まとめ

ヒト免疫不全ウイルス1型 (HIV-1) のトランス活性化タンパク質Tatは,TAR要素が機能するために特定のRNA二次構造を必要とします. これは,TatがHIV-1ゲノム発現中の新生RNAとしてTARを認識していることを示唆している.

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