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Updated: Apr 30, 2026

Chemical Modification of the Tryptophan Residue in a Recombinant Ca2+-ATPase N-domain for Studying Tryptophan-ANS FRET
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Chemical Modification of the Tryptophan Residue in a Recombinant Ca2+-ATPase N-domain for Studying Tryptophan-ANS FRET

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イオン化可能な活性部位トリプトファンは,過酸化酵素核にカタラーゼ活性を与える

Peter C Loewen1, Xavi Carpena, Pietro Vidossich

  • 1Department of Microbiology, University of Manitoba , Winnipeg MB R3T 2N2, Canada.

Journal of the American Chemical Society
|May 3, 2014
PubMed
まとめ

カタラーゼ過酸化酵素 (KatG) は,単一機能のカタラーゼを模倣して,活性部位のTrpデプロトネーションを介して過酸化水素を不釣り合いに変化させます. 移動性アルギニンは電子スイッチとして機能し,この重要な触媒的ステップを制御します.

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