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Updated: Apr 30, 2026

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
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サブストラット分解と酵素認識の非添加性

Sarah Barelier1, Jennifer A Cummings, Alissa M Rauwerdink

  • 1Department of Pharmaceutical Chemistry, University of California - San Francisco , 1700 Fourth Street, Byers Hall, San Francisco, California 94158, United States.

Journal of the American Chemical Society
|May 6, 2014
PubMed
まとめ

酵素基板の発見は困難です. 完全な基板ではなく,より小さな分子断片を用いた酵素の探査が調査されましたが,酵素の機能を特定するのに無効であることが判明しました. 酵素の研究には,完全な代謝産物のライブラリが推奨されます.

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