診断,管理,および学前期の喘息の予測
Francine M Ducharme1, Sze M Tse2, Bhupendrasinh Chauhan3
1Clinical Research and Knowledge Transfer on Childhood Asthma Unit, Research Centre, Sainte-Justine University Health Centre, Montreal, QC, Canada; Department of Paediatrics, University of Montreal, Montreal, QC, Canada; Department of Social and Preventive Medicine, University of Montreal, Montreal, QC, Canada.
Lancet (London, England)
|May 6, 2014
まとめ
幼稚園児の喘息は,長期的な肺機能に影響を及ぼす重大な健康上の課題です. 早期の介入と有効な治療法は,幼い子供のこの状態の管理に不可欠です.
科学分野:
- 小児肺病学について
- 呼吸器医学とは
- 子どもの健康 子どもの健康
背景:
- 幼稚園児の喘息は,診断上の課題であり,高齢者と比較して高い医療負担を伴う.
- 現存するフェノタイプ分類は,治療決定を導くための検証が欠けている.
- 遺伝的,産前および産後の要因は,学前期の喘息と関連しており,持続的な肺機能の欠損の可能性があります.
研究 の 目的:
- リスク要因,診断上の課題,治療アプローチを含む,学前期の喘息に関する現在の理解をレビューする.
- 幼稚園児の喘息が肺機能に及ぼす長期的な影響を強調する.
- 学前期の喘息の成果を改善するための研究優先事項を特定する.
主な方法:
- 学前期の喘息に関するコホート研究と臨床試験のレビュー.
- 危険因子,診断基準,治療効果の分析.
- 短期的および長期的結果に関する証拠の統合.
主要な成果:
- 幼稚園児の喘息は,幼児期から成人期までの持続的な肺機能の欠陥と関連しています.
- 毎日吸入するコルチコステロイドは,中間症状またはアトピーによる再発性喘息に有効です.
- 絶え間ない高用量の吸入用コルチコステロイドは,中間症状のない中等から重度のウイルス誘発性喘息に効果があります.
結論:
- 幼稚園児の喘息は,効果的な介入のための集中的な研究を必要とします.
- この状態に対処するために,検証された診断および治療戦略が必要です.
- 早期治療は,長期にわたる呼吸器系損傷を軽減する可能性があります.
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