,

Kazumitsu Onizuka1, Fumi Nagatsugi, Yoshihiro Ito

  • 1Nano Medical Engineering Laboratory, RIKEN , 2-1, Hirosawa, Wako, Saitama 351-0198, Japan.

まとめ

研究者らは,反応性オリゴデオキシリボヌクレオチド (ODN) を使用して,安定したDNAとRNAの擬似タキサン複合体を生成する新しい方法を開発しました. このブレークスルーは,DNAナノテクノロジーとアンチセンスオリゴヌクレオチド開発のための有望な新しい道を開く.

関連する概念動画

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Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids

Diols are compounds with two hydroxyl groups. In addition to syn dihydroxylation, diols can also be synthesized through the process of anti dihydroxylation. The process involves treating an alkene with a peroxycarboxylic acid to form an epoxide. Epoxides are highly strained three-membered rings with oxygen and two carbons occupying the corners of an equilateral triangle. This step is followed by ring-opening of the epoxide in the presence of an aqueous acid to give a trans diol.
Acid-Catalyzed α-Halogenation of Aldehydes and Ketones01:21

Acid-Catalyzed α-Halogenation of Aldehydes and Ketones

By replacing an α-hydrogen with a halogen, acid-catalyzed α-halogenation of aldehydes or ketones yields a monohalogenated product
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Base-Catalyzed Aldol Addition Reaction

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Diels–Alder Reaction Forming Cyclic Products: Stereochemistry

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Aldol Condensation with β-Diesters: Knoevenagel Condensation

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Nitrosation of Enols01:19

Nitrosation of Enols

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