抗精神病薬,気分安定剤,暴力犯罪のリスク
Seena Fazel1, Johan Zetterqvist2, Henrik Larsson2
1Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.
Lancet (London, England)
|May 13, 2014
まとめ
抗精神病薬と気分安定剤は,精神疾患の患者における暴力犯罪率を大幅に低下させた. これらの薬は,症状の緩和と再発の予防を超えて追加の利点を提供することができます.
科学分野:
- 精神科医は精神病を患っている.
- クリミノロジー 犯罪学
- 薬理学 薬理学とは
背景:
- 抗精神病薬や気分安定剤は,精神疾患に対して広く処方されています.
- 暴力犯罪の犯行に及ぼす影響は不明である.
- この研究では,精神病患者の暴力犯罪率に及ぼす影響を調査しています.
研究 の 目的:
- 暴力犯罪率に対する抗精神病薬と気分安定剤の効果を判断する.
- 混同因子を制御するために,個体内の薬物効果を分析する.
- 精神医学診断に基づく効果の潜在的な違いを評価する.
主な方法:
- 患者の処方箋,診断,および刑事有罪判決をリンクするスウェーデンの国家登録を活用した (2006-09).
- 薬物使用と非使用の間の犯罪率を比較する個人内分析を実施した.
- 主な結果:国家犯罪登録簿による暴力犯罪の発生.
主要な成果:
- 抗精神病薬 (HR 0.55) を服用すると暴力犯罪は45%,気分安定剤 (HR 0.76) を服用すると24%減少した.
- 気分安定剤は,双極性障害の患者においてのみ,暴力犯罪の減少を示した.
- 減少は抗精神病薬の投与量に依存し,デポ製剤の減少は顕著でした.
結論:
- 抗精神病薬と気分安定剤は,精神病患者の暴力犯罪率を低下させる可能性があります.
- これらの発見は,治療計画で考慮すべき追加の利点を示唆しています.
- 暴力の軽減における薬剤の役割は,精神疾患の管理において考慮されるべきである.
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