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Updated: Apr 29, 2026

Using In Vitro and In-cell SHAPE to Investigate Small Molecule Induced Pre-mRNA Structural Changes
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タンパク質のスポンジとして作用する非コーディングRNARsmZの構造的基礎

Olivier Duss1, Erich Michel1, Maxim Yulikov2

  • 1Institute of Molecular Biology and Biophysics, ETH Zürich, CH-8093 Zürich, Switzerland.

Nature
|May 16, 2014
PubMed
まとめ

RsmZのような非コーディングRNAは,タンパク質のスポンジとして作用し,細菌の毒性を制御するために規制タンパク質を隔離します. この研究は,Pseudomonas fluorescensのRsmEタンパク質ダイマーによるこの結合の分子機構を明らかにしています.

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