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複数のホルモンによって媒介されるインスリン分解酵素阻害剤の抗糖尿病作用

Juan Pablo Maianti1, Amanda McFedries1, Zachariah H Foda2

  • 1Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.

Nature
|May 23, 2014
PubMed
まとめ

新しいマクロサイクルでインスリン分解酵素 (IDE) を阻害すると,マウスのグルコース耐性および胃の排泄が改善されます. この発見は,2型糖尿病治療の新たな治療戦略の可能性を提示しています.

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