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ネイティブのEmrEの固有の形状の可塑性は,多剤耐性への経路を提供する

Min-Kyu Cho1, Anindita Gayen, James R Banigan

  • 1Department of Chemistry, New York University , New York, New York 10003, United States.

Journal of the American Chemical Society
|May 27, 2014
PubMed
まとめ

多剤耐性エフフルスポンプ EmrEは,ダイナミックな構造変化を示し,幅広い基板特異性を可能にします. 薬剤のない状態でより速いミリ秒の動き,基板への結合はなく,膜特性の変化を誘発する.

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