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Updated: Apr 29, 2026

Measuring Cell Cycle Progression Kinetics with Metabolic Labeling and Flow Cytometry
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Measuring Cell Cycle Progression Kinetics with Metabolic Labeling and Flow Cytometry

Published on: May 22, 2012

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サイクリンD1-Cdk4は,細胞サイクル進行とは無関係にグルコース代謝を制御する

Yoonjin Lee1, John E Dominy2, Yoon Jong Choi3

  • 11] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA [2] Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Nature
|May 30, 2014
PubMed
まとめ

インスリンは,サイクリンD1-Cdk4のような細胞サイクルタンパク質を使用して,PGC-1αアセチル化と肝臓のグルコース生成を調節することにより,グルコースレベルを制御し,糖尿病治療の新たな道を開きます.

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