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Updated: Apr 28, 2026

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry
08:07

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry

Published on: July 26, 2019

7.9K

PI4KIIIβ複合体の構造は,Rab11とそのエフェクターの同時募集を示しています

John E Burke1, Alison J Inglis2, Olga Perisic2

  • 1Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge CB2 0QH, UK. jeburke@uvic.ca rlw@mrc-lmb.cam.ac.uk.

Science (New York, N.Y.)
|May 31, 2014
PubMed
まとめ

構造は,Rab11a.のような小さなGTPasesとどのようにPhosphatidylinositol 4-キナーゼ (PI4Ks) が連携するかを明らかにします. この調整は膜の改造に不可欠であり,抗マラリア薬の開発に新たなターゲットを提供します.

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Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag

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Single-molecule Super-resolution Imaging of Phosphatidylinositol 4,5-bisphosphate in the Plasma Membrane with Novel Fluorescent Probes07:26

Single-molecule Super-resolution Imaging of Phosphatidylinositol 4,5-bisphosphate in the Plasma Membrane with Novel Fluorescent Probes

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