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Updated: Apr 28, 2026

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
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頭蓋内生殖細胞腫瘍における新しい体内および生殖細胞変異

Linghua Wang1, Shigeru Yamaguchi2, Matthew D Burstein3

  • 1Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas 77030, USA.

Nature
|June 5, 2014
PubMed
まとめ

頭蓋内生殖細胞腫瘍 (IGCTs) は,まれな脳がんである. ゲノム解析により,KIT/RASおよびAKT/mTOR経路の頻度の高い変異が明らかになり,この疾患に対する新しい治療標的が提供されています.

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