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Updated: Apr 28, 2026

Author Spotlight: THP-1 Macrophage Response to LPS/ATP — Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum
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Author Spotlight: THP-1 Macrophage Response to LPS/ATP — Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum

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アポプトティックなフォスファティジルセリンの被曝のために,フォスフォリピド・フリッパースのカスパーゼ媒介分裂

Katsumori Segawa1, Sachiko Kurata1, Yuichi Yanagihashi1

  • 1Department of Medical Chemistry, Graduate School of Medicine, Kyoto University, Yoshida-Konoe, Kyoto 606-8501, Japan.

Science (New York, N.Y.)
|June 7, 2014
PubMed
まとめ

ある研究では,ATP11CとCDC50Aが,細胞膜におけるフォスフォリピドの非対称性にとって極めて重要であることが判明しました. アポプトーシス中のフリッパース活性を非活性化すると,フォスファディチルセリンの暴露を防止し,マクロファージの吸収を阻害します.

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