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Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons
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人間のGABAA受容体の結晶構造

Paul S Miller1, A Radu Aricescu1

  • 1Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

Nature
|June 10, 2014
PubMed
まとめ

研究者らは,ヒトA型ガンマ-アミノバター酸受容体 (GABAAR) の最初の3D構造を明らかにした. この画期的な発見は,抑制性神経伝達と神経学的疾患に対する潜在的な薬物設計に関する新しい洞察を提供します.

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