関連する実験動画

Updated: Apr 28, 2026

Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation
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Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation

Published on: February 12, 2022

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移転RNAミミクリと,ウイルスRNAによる形状の可塑性の構造的基礎

Timothy M Colussi1, David A Costantino2, John A Hammond3

  • 11] Department of Biochemistry and Molecular Genetics, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA [2] Howard Hughes Medical Institute, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA [3] Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, USA (T.M.C.); Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, California 92037, USA (J.A.H.).

Nature
|June 10, 2014
PubMed
まとめ

ターニップ・イエロー・モザイクウイルス (TYMV) tRNAのような構造 (TLS) のRNAは,結晶構造を持ち,その双面的な性質を明らかにしています. このRNAは,片面でのアミノアシレーションのためのtRNAを模倣し,異なる面での他の機能を可能にし,その多機能性を説明します.

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