心臓病の子どもにおける累積的な放射線被曝とがんリスクの推定
Jason N Johnson1, Christoph P Hornik1, Jennifer S Li1
1From the Division of Pediatric Cardiology (J.N.J., C.P.H., J.S.L., K.D.H.) and Division of Radiology (T. T. Y., R.E.R., D.P.F.), Department of Pediatrics, Duke University Medical Center, Durham, NC; and Duke Clinical Research Institute, Durham, NC (J.S.L., D.K.B., K.D.H.).
Circulation
|June 11, 2014
まとめ
心臓病の子どもは,しばしば放射線画像検査を受ける. この研究では,全体的な放射線被曝が低いことが判明しましたが,特定のグループはより高いリスクに直面しており,特に高曝露画像検査では,投与量を減らす必要があります.
科学分野:
- ペディアトリック・カルディオロジー
- メディカルイマージング (医学イメージング)
- 放射線腫瘍学 放射線腫瘍学
背景:
- 心臓病の子どもは,頻繁に電離放射線を用いた画像検査を受けます.
- この集団における累積的な放射線被曝と関連する癌のリスクに関するデータは限られている.
研究 の 目的:
- 心臓病の小児におけるすべての検査による累積的な有効放射線量を評価する.
- この曝露に関連した生涯に起因する癌のリスクを推定する.
主な方法:
- 2005年から2010年の間に心臓手術を受けた337人の子供 (≤6歳) のコホートが研究されました.
- 累積有効用量 (mSv) は13,932回の放射線検査から計算された.
- 生涯に起因するがんリスクは,電離放射線の生物学的影響委員会VIIのアプローチを用いて推定されました.
主要な成果:
- 従来のX線写真検査は検査の92%を占めたが,心経 катетеризацияとCTスキャンは累積用量の81%を占めた.
- 平均累積有効用量は2.7mSvで,生涯がんリスクの平均値は0.07%でした.
- 癌のリスクは手術の複雑さによって変化し,女性では有効用量の1単位あたりより高かった.
結論:
- 小児性心疾患患者の放射線被曝量は一般的に低い.
- 特定の患者コホートは,相当な放射線量を受け,注意を払う必要がある.
- 放射線量,特に高曝露イメージング方式からの放射線量を制限することは,がんのリスク軽減に不可欠です.
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