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A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
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A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species

Published on: August 16, 2018

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ルイス塩基触媒,エナチオセレクティブ,オレフィンの分子内硫フェノアミナ化

Scott E Denmark1, Hyung Min Chi

  • 1Department of Chemistry, University of Illinois Urbana-Champaign , Urbana, Illinois 61801, United States.

Journal of the American Chemical Society
|June 14, 2014
PubMed
まとめ

新しい触媒的方法により,オレフィンのエナチオセレクティブスルフェノアミネーションが可能になり,高ステレオセレクティブ性のピロリジン,ピペリジン,アゼパンが得られます. このブレークスルーは,価値あるヘテロサイクリック化合物の効率的な合成のために,キラルルイス塩基触媒を使用しています.

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