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心筋収縮機能不全は,2型糖尿病患者のミトコンドリア機能と動態の障害と関連しているが,肥満患者の場合はそうではない

David Montaigne1, Xavier Marechal2, Augustin Coisne2

  • 1From the Department of Physiology, Faculty of Medicine Lille, Lille, France (D.M., X.M., A.C., N.D., C.P., S.M., S.P., R.N.); Service d'Explorations Fonctionnelles CardioVasculaires (D.M., A.C., S.M.), Department of Cardiovascular Surgery (T.M., G.F., J.-M.E.A., M.K.), and Biochemistry Division, Pathology and Biology Center (F.Z.), University Hospital of Lille, Lille, France; Université Lille 2, Inserm, U1011, and Institut Pasteur de Lille, Lille, France (D.M., X.M., Y.S., H.D., P.L., B.S.); University Hospital of Lille, Lille, France; INSERM U1096, University of Rouen, Institute for Research and Innovation in Biomedicine, Rouen, France (I.R.-J., V.R.); and EA4483-Département de Médecine du Travail, Faculty of Medicine; University Lille 2, Lille, France (J.-L.E.). davidmontaigne@hotmail.com bart.staels@pasteur-lille.fr.

Circulation
|June 15, 2014
PubMed
まとめ

糖尿病は,心不全が発症する前に,心筋収縮とミトコンドリア機能を著しく損なう. 肥満だけでは,心臓機能とミトコンドリアに与える影響は少ない.

キーワード:
オートファジー (Autophagy) とは糖尿病 メリツス,タイプ2ミトコンドリア ミトコンドリアミトコンドリアのダイナミクス肥満 肥満 肥満

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