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アリル炭化水素受容体の病気耐性防御経路の制御

Alban Bessede1, Marco Gargaro2, Maria T Pallotta3

  • 11] Department of Experimental Medicine, University of Perugia, 06132 Perugia, Italy [2] IMS Laboratory, University of Bordeaux, 33607 Pessac, France [3].

Nature
|June 17, 2014
PubMed
まとめ

リポポリサッカリド (LPS) によってアリル炭水化物受容体 (AhR) を活性化すると,最初は炎症が軽減されます. この経路は,再挑戦時にインドロアミン2,3-二酸化酵素1 (IDO1) を関与させ,内毒素耐性を促進し,感染から保護します.

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