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Updated: May 5, 2026

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
15:07

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma

Published on: December 28, 2015

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鶏のIgL遺伝子の再編成は,円形エピソームの削除と,両方のコーディングセグメントに単一の非ランダムなニュクレオチドの追加を含みます

W T McCormack1, L W Tjoelker, L M Carlson

  • 1Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor 48109.

Cell
|March 10, 1989
PubMed
まとめ

鶏の免疫グロブリン軽鎖 (IgL) 遺伝子再配列には,DNAの削除とエピソーム形成が含まれます. このプロセスは,コーディングセグメントに塩基を追加し,B細胞発達の過程で,様々なV-J結合配列につながります.

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