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Updated: Apr 27, 2026

PCR Mutagenesis, Cloning, Expression, Fast Protein Purification Protocols and Crystallization of the Wild Type and Mutant Forms of Tryptophan Synthase
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Thymidylate synthaseにおける協調対段階的なメカニズム

Zahidul Islam1, Timothy S Strutzenberg, Ilya Gurevic

  • 1Department of Chemistry, The University of Iowa , Iowa City, Iowa 52242-1727, United States.

Journal of the American Chemical Society
|June 21, 2014
PubMed
まとめ

この研究では,チミジラート合成酵素 (TSase) の反応機構を調査しています. 発見は,ヒドリド移転のための協調的なメカニズムを支持し,活性部位アルギニンの触媒作用の役割を強調しています.

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