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Updated: Apr 27, 2026

In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice
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Published on: November 22, 2017

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糖尿病感受性遺伝子Clec16aは,ミトファギーを調節する

Scott A Soleimanpour1, Aditi Gupta2, Marina Bakay3

  • 1Division of Endocrinology, Diabetes and Metabolism, Department of Medicine and the Institute for Diabetes, Obesity and Metabolism of the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA; Division of Metabolism, Endocrinology & Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48105, USA.

Cell
|June 21, 2014
PubMed
まとめ

Clec16aタンパク質は,ミトファギーを調節することにより,臓のβ細胞機能と糖尿病予防に不可欠です. Clec16aの減少は,インスリン分泌とミトコンドリアの健康を損なっており,グルコース代謝に影響します.

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